In contrast, the cumulative spontaneous locomotor activity of mice treated with the essential oil or hydroalcoholic extract was significantly decreased. odoratissima changed the percentage of the time spent or number of entries into the open arms of the elevated plus maze. The anxiolytic and sedative effects were determined by an elevated plus maze and locomotor activity tests, respectively.Īccording to the results, none of the administered doses of hydroalcoholic extract or essential oil fraction of K. The hydroalcoholic extract or essential oil fraction from this plant were administered intraperitoneally to male mice at various doses 30 min before testing. The chemical composition of its essential oil was also determined.
odoratissima) in mice by utilizing an elevated plus maze. The present study aimed to evaluate the sedative and anxiolytic effects of the essential oils and hydroalcoholic extract of Kelussia odoratissima Mozaff.
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